Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased BDNF levels and NTRK2 gene association suggest a disruption of BDNF/TrkB signaling in autism.

Genes, brain, and behavior - 1 Oct 2010

Correia C T, Coutinho A M, Sequeira A F, Sousa I G, Lourenço Venda L, Almeida J P, Abreu R L, Lobo C, Miguel T S, Conroy J, Cochrane L, Gallagher L, Gill M, Ennis S, Oliveira G G, Vicente A M

Abstract excerpt

The brain-derived neurotrophic factor (BDNF), a neurotrophin fundamental for brain development and function, has previously been implicated in autism. In this study, the levels of BDNF in platelet-rich plasma were compared between autistic and control children, and the role of two genetic factors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autistic Disorder
Share to Blood Platelets

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Child, Preschool

Share to Haplotypes

Share to Receptor, trkB

Share to Signal Transduction

Source

Identifiers

PMID: 20662941
DOI: 10.1111/j.1601-183X.2010.00627.x

Genes

BDNF
NTRK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20662941-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased BDNF levels and NTRK2 gene association suggest a disruption of BDNF/TrkB signaling in autism.PMID 20662941Read ↗

Genetic analyses of the brain-derived neurotrophic factor (BDNF) gene in autism.Semantic proximity Read ↗

Evidence for epistasis between SLC6A4 and ITGB3 in autism etiology and in the determination of platelet serotonin levels.Semantic proximity Read ↗

Variants of the serotonin transporter gene (SLC6A4) significantly contribute to hyperserotonemia in autism.Semantic proximity Read ↗

The involvement of serotonin polymorphisms in autistic spectrum symptomatology.Semantic proximity Read ↗

Genetic association and gene-gene interaction analyses suggest likely involvement of ITGB3 and TPH2 with autism spectrum disorder (ASD) in the Indian population.Semantic proximity Read ↗

Serotonin transporter gene polymorphisms and hyperserotonemia in autistic disorder.Semantic proximity Read ↗

Association of NTRK2 gene with suicidality: a meta-analysis.Semantic proximity Read ↗

Is autism caused by early hyperactivity of brain-derived neurotrophic factor?Semantic proximity Read ↗

Hyperserotonemia in autism: the potential role of 5HT-related gene variants.Semantic proximity Read ↗

Increased expression of BDNF mRNA in the frontal cortex of autistic patients.Semantic proximity Read ↗

Serotonin transporter promoter variants: Analysis in Indian autistic and control population.Semantic proximity Read ↗

SLC6A4 markers modulate platelet 5-HT level and specific behaviors of autism: a study from an Indian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.