Article
Genetic analyses of the brain-derived neurotrophic factor (BDNF) gene in autism.
Biochemical and biophysical research communications - 27 Apr 2007
Nishimura Katsuhiko, Nakamura Kazuhiko, Anitha A, Yamada Kazuo, Tsujii Masatsugu, Iwayama Yoshimi, Hattori Eiji, Toyota Tomoko, Takei Nori, Miyachi Taishi, Iwata Yasuhide, Suzuki Katsuaki, Matsuzaki Hideo, Kawai Masayoshi, Sekine Yoshimoto, Tsuchiya Kenji, Sugihara Gen-ichi, Suda Shiro, Ouchi Yasuomi, Sugiyama Toshiro, Yoshikawa Takeo, Mori Norio
Abstract excerpt
Autism is a severe neurodevelopmental disorder defined by social and communication deficits and ritualistic-repetitive behaviors that are detectable in early childhood. Brain-derived neurotrophic factor (BDNF) plays a critical role in the pathogenesis of autism. In this study, we examined the SNP- and haplotypic-association of BDNF with autism in a trios-based association study (the Autism Genetic Resource...
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