Article
Sampling the solution space in genome-scale metabolic networks reveals transcriptional regulation in key enzymes.
PLoS computational biology - 15 Jul 2010
Bordel Sergio, Agren Rasmus, Nielsen Jens
Abstract excerpt
Genome-scale metabolic models are available for an increasing number of organisms and can be used to define the region of feasible metabolic flux distributions. In this work we use as constraints a small set of experimental metabolic fluxes, which reduces the region of feasible metabolic states....
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