Article
Early origin and recent expansion of Plasmodium falciparum.
Science (New York, N.Y.) - 11 Apr 2003
Joy Deirdre A, Feng Xiaorong, Mu Jianbing, Furuya Tetsuya, Chotivanich Kesinee, Krettli Antoniana U, Ho May, Wang Alex, White Nicholas J, Suh Edward, Beerli Peter, Su Xin-zhuan
Abstract excerpt
The emergence of virulent Plasmodium falciparum in Africa within the past 6000 years as a result of a cascade of changes in human behavior and mosquito transmission has recently been hypothesized. Here, we provide genetic evidence for a sudden increase in the African malaria parasite population about 10,000 years ago, followed by migration to other regions on the basis of variation in 100 worldwide mitochondrial...
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