Article
Telomere biology in Metazoa.
FEBS letters - 10 Sept 2010
Gomes Nuno M V, Shay Jerry W, Wright Woodring E
Abstract excerpt
In this review we present critical overview of some of the available literature on the fundamental biology of telomeres and telomerase in Metazoan. With the exception of Nematodes and Arthropods, the (TTAGGG)(n) sequence is conserved in most Metazoa. Available data show that telomerase-based end maintenance is a very ancient mechanism in unicellular and multicellular organisms. In invertebrates, fish, amphibian,...
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