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Article

A mutant receptor with enhanced dominant-negative activity for the blockade of human prolactin signalling.

Journal of molecular endocrinology - 1 Apr 2004

Flynn A, Whittington H, Goffin V, Uney J, Norman M

Abstract excerpt

An effective mechanism for interfering with prolactin signalling would provide a powerful tool for clarifying the importance of prolactin in breast cancer, as well as for investigating functions of prolactin in other tissues. Based on our previous identification of a dominant-negative mutation in the growth hormone receptor that causes familial short stature, we investigated the potential for using a similar...

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Identifiers

PMID: 15072546
DOI: 10.1677/jme.0.0320385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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