Article
Issues surrounding the assessment of the genetic determinants of drugs as reinforcing stimuli.
Journal of addictive diseases - 1 Jan 1991
Carney J M, Cheng M S, Wu C, Seale T W
Abstract excerpt
A wide variety of drugs used in medicine and on a non-prescription basis have abuse liability. However, not all psychoactive drugs have demonstrable reinforcing properties either in animal models or in humans. In order to predict the abuse liability of a compound or to understand determinants of...
Topics
- Animals
- Genotype
- Mice
- Mice, Inbred Strains
- Models, Genetic
- Psychotropic Drugs
- Substance-Related Disorders
