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Exposure of human fallopian tube epithelium to elevated testosterone results in alteration of cilia gene expression and beating

5 Jun 2020

Abstract excerpt

STUDY QUESTION: How does exposure to a testosterone rich environment affect the function and gene expression of human fallopian tube epithelium (hFTE)? SUMMARY ANSWER: Elevated testosterone level alters several gene transcripts that regulate cilia expression and negatively impacts the rate of cilia beating. WHAT IS KNOWN ALREADY: The presence of estrogen in the follicular phase of the menstrual cycle increases...

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Share to Ovarian cancer diagnosis and treatment
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PMID: 32756960
DOI: 10.1093/humrep/deaa157

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