Article
Systemic transplantation of c-kit+ cells exerts a therapeutic effect in a model of amyotrophic lateral sclerosis.
Human molecular genetics - 1 Oct 2010
Corti Stefania, Nizzardo Monica, Nardini Martina, Donadoni Chiara, Salani Sabrina, Simone Chiara, Falcone Marianna, Riboldi Giulietta, Govoni Alessandra, Bresolin Nereo, Comi Giacomo P
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, neurodegenerative disease characterized by the loss of motor neurons. Motor neuron degeneration is probably both a cell autonomous and a non-autonomous event. Therefore, manipulating the diseased microenvironment via non-neural cell rep...
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