Article
Melanocytic nevi, nevus genes, and melanoma risk in a large case-control study in the United Kingdom.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2010
Newton-Bishop Julia A, Chang Yu-Mei, Iles Mark M, Taylor John C, Bakker Bert, Chan May, Leake Susan, Karpavicius Birute, Haynes Sue, Fitzgibbon Elaine, Elliott Faye, Kanetsky Peter A, Harland Mark, Barrett Jennifer H, Bishop D Timothy
Abstract excerpt
BACKGROUND: Increased number of melanocytic nevi is a potent melanoma risk factor. We have carried out a large population-based case-control study to explore the environmental and genetic determinants of nevi and the relationship with melanoma risk. METHODS: We report nevus phenotype in relation to differing patterns of sun exposure, inherited variation at loci shown in recent genome-wide association studies to...
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