Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Interplay between Nevi and Melanoma Predisposition Unravels Nevi-Related and Nevi-Resistant Familial Melanoma.

Genes - 16 Jul 2021

Pellegrini Stefania, Elefanti Lisa, Dall'Olmo Luigi, Menin Chiara

Abstract excerpt

Genetic susceptibility to nevi may affect the risk of developing melanoma, since common and atypical nevi are the main host risk factors implicated in the development of cutaneous melanoma. Recent genome-wide studies defined a melanoma polygenic risk score based on variants in genes involved in different pathways, including nevogenesis. Moreover, a predisposition to nevi is a hereditary trait that may account for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Melanoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma, Cutaneous Malignant

Share to Penetrance

Share to Phenotype

Share to Risk Factors

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 34356093
DOI: 10.3390/genes12071077
PMCID: PMC8303673

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Interplay between Nevi and Melanoma Predisposition Unravels Nevi-Related and Nevi-Resistant Familial Melanoma.PMID 34356093Read ↗

Genetics of cutaneous melanoma and nevi.Semantic proximity Read ↗

Genetic Landscape of Familial MelanomaSemantic proximity Read ↗

Influence of germline genetic variants on dermoscopic features of melanoma.Semantic proximity Read ↗

Genetic predisposition to melanoma.Semantic proximity Read ↗

Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility.Semantic proximity Read ↗

A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma.Semantic proximity Read ↗

The genetics of hereditary melanoma and nevi. 1998 update.Semantic proximity Read ↗

Nevi and Melanoma.Semantic proximity Read ↗

Multiplex melanoma families are enriched for polygenic risk.Semantic proximity Read ↗

Genetic architecture of multiple primary cutaneous melanoma in the absence of high-penetrance susceptibility genes.Semantic proximity Read ↗

Melanoma genetics: a review of genetic factors and clinical phenotypes in familial melanoma.Semantic proximity Read ↗

Influence of genes, nevi, and sun sensitivity on melanoma risk in a family sample unselected by family history and in melanoma-prone families.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.