Article
Apigenin inhibits larval growth of Caenorhabditis elegans through DAF-16 activation.
FEBS letters - 20 Aug 2010
Kawasaki Ichiro, Jeong Myung-Hwan, Oh Bong-Kyeong, Shim Yhong-Hee
Abstract excerpt
Treatment of Caenorhabditis elegans with apigenin, 5,7,4'-trihydroxyflavone, induces larval growth inhibition. To understand the molecular basis of apigenin-induced larval growth inhibition, the effects of apigenin on DAF-16 activity were examined. DAF-16 was activated through nuclear translocati...
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