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Article

HFE gene mutations increase the risk of coronary heart disease in women.

European journal of epidemiology - 1 Sept 2010

Pardo Silva M Carolina, Njajou Omer T, Alizadeh Behrooz Z, Hofman Albert, Witteman Jacqueline C M, van Duijn Cornelia M, Janssens A Cecile J W

Abstract excerpt

The purpose of the present study is to examine HFE gene mutations in relation to newly diagnosed (incident) coronary heart disease (CHD). In a population-based follow-up study of 7,983 individuals aged 55 years and older, we compared the risk of incident CHD between HFE carriers and non-carriers, overall and stratified by sex and smoking status. HFE mutations were significantly associated with an increased risk...

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Source

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Identifiers

PMID: 20640879
DOI: 10.1007/s10654-010-9489-6
PMCID: PMC2931632

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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