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Article

Prevalence of coronary heart disease associated with HFE mutations in adults attending a health appraisal center.

The American journal of medicine - 15 Oct 2002

Waalen Jill, Felitti Vincent, Gelbart Terri, Ho Ngoc J, Beutler Ernest

Abstract excerpt

PURPOSE: Mutations of the HFE gene that cause hereditary hemochromatosis may be associated with an increased risk of cardiovascular disease. We examined the relation between two HFE mutations (C282Y and H63D), indicators of iron homeostasis, and the prevalence of coronary heart disease in a large population of white adults. SUBJECTS AND METHODS: We conducted a cross-sectional study of 30,916 white adults aged 25...

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Source

Identifiers

PMID: 12427496
DOI: 10.1016/s0002-9343(02)01249-4

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Prevalence of coronary heart disease associated with HFE mutations in adults attending a health appraisal center.PMID 12427496Read ↗

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A prospective study of coronary heart disease and the hemochromatosis gene (HFE) C282Y mutation: the Atherosclerosis Risk in Communities (ARIC) study.Semantic proximity Read ↗

HFE C282Y homozygosity is associated with lower total and low-density lipoprotein cholesterol: The hemochromatosis and iron overload screening study.Semantic proximity Read ↗

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