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Article

Additive effects of serotonin transporter and tryptophan hydroxylase-2 gene variation on emotional processing.

Cerebral cortex (New York, N.Y. : 1991) - 1 May 2007

Herrmann Martin J, Huter Theresa, Müller Frauke, Mühlberger Andreas, Pauli Paul, Reif Andreas, Renner Tobias, Canli Turhan, Fallgatter Andreas J, Lesch Klaus-Peter

Abstract excerpt

Prior studies reported that functional variants of both the serotonin transporter (5-HTT) and tryptophan hydroxylase-2 genes (TPH2), 2 key regulators of the serotonergic signaling pathway, modulate amygdala activation during emotional processing. We addressed the question whether these 2 gene variants modulate each other, using an emotional picture-processing task. Specifically, we measured event-related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Serotonin Plasma Membrane Transport Proteins

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Source

Identifiers

PMID: 16801378
DOI: 10.1093/cercor/bhl026

Genes

HTT
TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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