It's the machine that matters: Predicting gene function and phenotype from protein networks.

Abstract excerpt

Increasing knowledge about the organization of proteins into complexes, systems, and pathways has led to a flowering of theoretical approaches for exploiting this knowledge in order to better learn the functions of proteins and their roles underlying phenotypic traits and diseases. Much of this body of theory has been developed and tested in model organisms, relying on their relative simplicity and genetic and...

Topics

• Animals
• Disease
• Humans
• Neoplasms
• Phenotype
• Proteins
• Proteomics