Article
EGFR inhibitors: what have we learned from the treatment of lung cancer?
Nature clinical practice. Oncology - 1 Nov 2005
Giaccone Giuseppe, Rodriguez Jose Antonio
Abstract excerpt
Tyrosine kinase inhibitors directed against the epidermal growth factor receptor (EGFR) are the first molecular-targeted agents to be approved in the US and other countries for the treatment of advanced non-small-cell lung cancer after failure of chemotherapy. Some patient characteristics, such as never-smoking, female gender, East Asian origin, adenocarcinoma histology, and bronchioloalveolar subtype, are...
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