Clinical and testing protocols for the analysis of epidermal growth factor receptor mutations in East Asian patients with non-small cell lung cancer: a combined clinical-molecular pathological approach.

doi:10.1097/JTO.0b013e318227816a

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Article

Clinical and testing protocols for the analysis of epidermal growth factor receptor mutations in East Asian patients with non-small cell lung cancer: a combined clinical-molecular pathological approach.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2011

Salto-Tellez Manuel, Tsao Ming-Sound, Shih Jin-Yuan, Thongprasert Sumitra, Lu Shun, Chang Gee-Chen, Au Joseph Siu-Kie, Chou Teh-Ying, Lee Jong-Seok, Shi Yuan-Kai, Radzi Ahmad, Kang Jin-Hyoung, Kim Sang-We, Tan Soo-Yong, Yang James Chih-Hsin

Abstract excerpt

BACKGROUND: Several randomized phase III studies in advanced stage non-small cell lung cancer (NSCLC) confirmed the superior response rate and progression-free survival of using epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor as first-line therapy compared with chemotherapy in patients with activating EGFR mutations. Despite the need for EGFR mutation tests to guide first-line therapy in East...

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PMID: 21869714
DOI: 10.1097/JTO.0b013e318227816a

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EGFR

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