Article
Confirmation of LRRK2 S1647T variant as a risk factor for Parkinson's disease in southern China.
European journal of neurology - 1 Mar 2011
Zheng Y, Liu Y, Wu Q, Hong H, Zhou H, Chen J, Wang H, Xian W, Li J, Liu Z, Pei Z, Chen L
Abstract excerpt
BACKGROUND: Leucine-rich repeat kinase 2 (LRRK2) S1647T has been identified as a risk variant for Parkinson's disease (PD) in Han Chinese. METHODS: To replicate the association of LRRK2 S1647T with risk of PD, we conducted a case-control study of this variant involving 406 PD subjects and 412 controls from southern mainland China. RESULTS: The results showed that the frequency of A allele was higher in patients...
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