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Article

Low Frequency of Epigenetic Events in Urothelial Tumors in Young Patients

18 Jun 2010

Abstract excerpt

PURPOSE: Bladder urothelial cell carcinoma is uncommon in young patients. We recently reported a series of tumors in patients younger than 20 years at diagnosis and performed exhaustive genetic screening for molecular alterations. Few events typical of bladder urothelial cell carcinoma were detected. Since many carcinogenic events occur at the epigenetic rather than the genetic level, we analyzed the same tumors...

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Share to Bladder and Urothelial Cancer Treatments
Share to Epigenetics and DNA Methylation
Share to Urinary and Genital Oncology Studies

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Identifiers

PMID: 20620398
DOI: 10.1016/j.juro.2010.03.131

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