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Article

HRAS mutations in bladder cancer at an early age and the possible association with the Costello Syndrome.

European journal of human genetics : EJHG - 1 Jun 2014

Beukers Willemien, Hercegovac Aleksander, Zwarthoff Ellen C

Abstract excerpt

Bladder tumours of patients <20 years have a low incidence of genetic aberrations typically found in tumours in older patients. In this study, we investigated oncogene mutations in patients with bladder cancer (BC) <20 years and compared them to older age groups. Interestingly, we observed a relatively high number of HRAS mutations in tumour from young patients. These mutations were also highly uncommon in BCs of...

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Source

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Identifiers

PMID: 24169525
DOI: 10.1038/ejhg.2013.251
PMCID: PMC4023225

Genes

HRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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