Article
Reduction potential variations in azurin through secondary coordination sphere phenylalanine incorporations.
Journal of inorganic biochemistry - 1 Oct 2010
Berry Steven M, Baker Madelyn H, Reardon Nicole J
Abstract excerpt
Recent evidence has shown that the properties of metal binding sites can be tuned by more than the ligands in the primary coordination sphere. We investigated the incorporation of four phenylalanine residues into the secondary coordination sphere of the small soluble blue copper protein azurin. The locations for placement of these residues in azurin were based on the structure of the highly hydrophobic blue...
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