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Stem Cell Models of Cardiac Development and Disease

7 Oct 2010

Abstract excerpt

The past few years have witnessed remarkable advances in stem cell biology and human genetics, and we have arrived at an era in which patient-specific cell and tissue models are now practical. The recent identification of cardiovascular progenitor cells, as well as the identification of genetic variants underlying congenital heart disorders and adult disease, opens the door to the development of human models of...

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PMID: 20604707
DOI: 10.1146/annurev-cellbio-100109-103948

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