Article
Induced pluripotent stem cells in cardiovascular drug discovery.
Circulation research - 1 Feb 2013
Mercola Mark, Colas Alexandre, Willems Erik
Abstract excerpt
The unexpected discovery that somatic cells can be reprogrammed to a pluripotent state yielding induced pluripotent stem cells has made it possible to produce cardiovascular cells exhibiting inherited traits and disorders. Use of these cells in high throughput analyses should broaden our insight into fundamental disease mechanisms and provide many benefits for patients, including new therapeutics and individually...
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