Article
DNA damage and repair in endometrial cancer in correlation with the hOGG1 and RAD51 genes polymorphism.
Molecular biology reports - 1 Feb 2011
Krupa Renata, Sobczuk Anna, Popławski Tomasz, Wozniak Katarzyna, Blasiak Janusz
Abstract excerpt
The cellular reaction to the DNA-damaging agents may modulate individual's cancer susceptibility. This reaction is mainly determined by the efficacy of DNA repair, which in turn, may be influenced by the variability of DNA repair genes, expressed by their polymorphism. The hOGG1 gene encodes a glycosylase of base excision repair and RAD51 specifies a key protein in homologues recombination repair. Both proteins...
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