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Article

Sodium channels and the neurobiology of epilepsy.

Epilepsia - 1 Nov 2012

Oliva Megan, Berkovic Samuel F, Petrou Steven

Abstract excerpt

Voltage-gated sodium channels (VGSCs) are integral membrane proteins. They are essential for normal neurologic function and are, currently, the most common recognized cause of genetic epilepsy. This review summarizes the neurobiology of VGSCs, their association with different epilepsy syndromes, and the ways in which we can experimentally interrogate their function. The most important sodium channel subunit of...

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Identifiers

PMID: 22905747
DOI: 10.1111/j.1528-1167.2012.03631.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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