Channels active in the excitability of nerves and skeletal muscles across the neuromuscular junction: basic function and pathophysiology

Abstract excerpt

Ion channels are essential for the basic physiological function of excitable cells such as nerve, skeletal, cardiac, and smooth muscle cells. Mutations in genes that encode ion channels have been identified to cause various diseases and disorders known as channelopathies. An understanding of how individual ion channels are involved in the activation of motoneurons and their corresponding muscle cells is essential...

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