Fast and accurate estimation of the population-scaled mutation rate, theta, from microsatellite genotype data.

Abstract excerpt

We present a new approach for estimation of the population-scaled mutation rate, , from microsatellite genotype data, using the recently introduced "product of approximate conditionals" framework. Comparisons with other methods on simulated data demonstrate that this new approach is attractive in terms of both accuracy and speed of computation. Our simulation experiments also demonstrate that, despite the...

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