Article

Potential of Recombinant Chimeric HPV16 L1/L2 VLPs Produced by Distinct Cell Lineages Such as Prophylactic Nanovaccine and Therapeutic Drug Nanocarriers

2025-03-12

Abstract excerpt

Human Papillomavirus (HPV) causes anogenital warts and six types of cancer in infected women, men, or children, being a challenge to global public health. HPV capsid is composed of viral type-specific L1 and evolutionarily conserved L2 proteins. Produced in heterologous systems, L1 protein can self-assemble into virus-like particles (VLPs), nanoparticles sizing around 50-60 nm, used as prophylactic vaccines. Devoi...

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Literature Corpus work: 3fb22a4f-d8a6-5847-81c7-cd5ef986831e
DOI: 10.20944/preprints202503.0817.v1

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