Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The pro-migratory and pro-invasive role of the procoagulant tissue factor in malignant gliomas.

Cell adhesion & migration - 1 Jan 2000

Dützmann Stephan, Gessler Florian, Harter Patrick N, Gerlach Rüdiger, Mittelbronn Michel, Seifert Volker, Kögel Donat

Abstract excerpt

During the infiltration process, glioma cells are known to migrate along preexisting anatomical structures such as blood vessels, axonal fiber tracts and the subependymal space, thereby widely invading surrounding CNS tissue. This phenomenon represents a major obstacle for the clinical treatment of these tumours. Several extracellular key factors and intracellular signaling pathways have been previously linked to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Hypoxia
Share to Glioma

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Necrosis

Share to Neoplasm Invasiveness

Share to Neoplastic Stem Cells

Share to Thromboplastin

Share to Thrombosis

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 20595809
DOI: 10.4161/cam.4.4.12660
PMCID: PMC3011255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The pro-migratory and pro-invasive role of the procoagulant tissue factor in malignant gliomas.PMID 20595809Read ↗

Insights in the immunobiology of glioblastoma.Semantic proximity Read ↗

Matrix metalloproteinases and their biological function in human gliomasSemantic proximity Read ↗

Understanding the Role of Endothelial Cells in Glioblastoma: Mechanisms and Novel TreatmentsSemantic proximity Read ↗

Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells.Semantic proximity Read ↗

Turning attention to tumor–host interface and focus on the peritumoral heterogeneity of glioblastomaSemantic proximity Read ↗

The glioblastoma vasculature as a target for cancer therapySemantic proximity Read ↗

Mechanisms of tumor cell invasion and angiogenesis in the central nervous systemSemantic proximity Read ↗

Tumor-Derived Pericytes Driven by EGFR Mutations Govern the Vascular and Immune Microenvironment of Gliomas.Semantic proximity Read ↗

Chemokine signaling in tumors: potential role of CXC chemokines and their receptors as glioblastoma therapeutic targetsSemantic proximity Read ↗

Epidermal growth factor receptor - mediated signal transduction in the development and therapy of gliomas.Semantic proximity Read ↗

A dual pronged approach to cancer immune exclusion: tumor-derived LAIR-1 simultaneously drives fibrosis and blocks immune recruitment in gliomaSemantic proximity Read ↗

Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.