Article
Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations.
Proceedings of the National Academy of Sciences of the United States of America - 4 Mar 2014
Magnus Nathalie, Garnier Delphine, Meehan Brian, McGraw Serge, Lee Tae Hoon, Caron Maxime, Bourque Guillaume, Milsom Chloe, Jabado Nada, Trasler Jacquetta, Pawlinski Rafal, Mackman Nigel, Rak Janusz
Abstract excerpt
The coagulation system links immediate (hemostatic) and late (inflammatory, angiogenic) tissue responses to injury, a continuum that often is subverted in cancer. Here we provide evidence that tumor dormancy is influenced by tissue factor (TF), the cancer cell-associated initiator of the coagulat...
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