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Article

Methylation matters: interaction between methylation density and serotonin transporter genotype predicts unresolved loss or trauma.

Biological psychiatry - 1 Sept 2010

van IJzendoorn Marinus H, Caspers Kristin, Bakermans-Kranenburg Marian J, Beach Steven R H, Philibert Robert

Abstract excerpt

BACKGROUND: Do genetic or epigenetic factors play a role in making some individuals more vulnerable than others to loss of attachment figures or other traumatic experiences? METHODS: DNA was obtained from growth phase entrained Epstein-Barr Virus (EBV) transformed lymphoblast cell lines from 143 adopted participants. Genotype of the serotonin transporter linked polymorphic region (5HTTLPR) was determined, and...

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Identifiers

PMID: 20591416
DOI: 10.1016/j.biopsych.2010.05.008
PMCID: PMC2921470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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