Article
A study of Adenosine-Deaminase genetic polymorphism in rheumatoid arthritis.
International journal of immunopathology and pharmacology - 1 Jan 2000
Sebastiani G D, Bottini N, Greco E, Saccucci P, Canu G, Lucarelli P, Gloria-Bottini F, Fontana L
Abstract excerpt
Recent investigations suggest that Adenosine Deaminase (ADA) could play a role in susceptibility to rheumatoid arthritis (RA). The purpose of our study is to investigate the possible role of genetic variability of ADA in the susceptibility to RA. We studied three intragenic ADA polymorphisms, ADA1, ADA2 and ADA6, in a sample of 91 subjects with RA and in 246 healthy subjects from the same Caucasian population and...
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