Article
Serum Uric Acid in LRRK2 Related Parkinson's Disease: Longitudinal Data from the PPMI Study.
Journal of Parkinson's disease - 1 Jan 2021
Bougea Anastasia, Koros Christos, Papagiannakis Nikolaos, Simitsi Athina-Maria, Prentakis Andreas, Papadimitriou Dimitra, Pachi Ioanna, Antonelou Roubina, Angelopoulou Efthalia, Beratis Ion, Bozi Maria, Papageorgiou Sokratis G, Trapali Xenia Geronicola, Stamelou Maria, Stefanis Leonidas
Abstract excerpt
BACKGROUND: Previous studies have highlighted serum uric acid as a putative idiopathic Parkinson's disease (iPD) biomarker. Only one study, so far, showed higher levels of serum uric acid in leucine-rich repeat kinase 2 (LRRK + 2) carriers compared to those who developed PD, however a longitudinal comparison between LRRK2 + PD and healthy controls (HC) has not been performed. OBJECTIVE: The aim of this study was...
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