Article
Evaluation of 28 human embryonic stem cell lines for use as unrelated donors in stem cell therapy: implications of HLA and ABO genotypes.
Cell transplantation - 1 Jan 2010
Lee Jeoung Eun, Kang Myung Seo, Park Myoung Hee, Shim Sung Han, Yoon Tae Ki, Chung Hyung Min, Lee Dong Ryul
Abstract excerpt
For human embryonic stem cells (hESCs) to be used clinically, it is imperative that immune responses evoked by hESCs and their derivates after transplantation should be prevented. Human leukocyte antigens (HLA) and ABO blood group antigens are important histocompatibility factors in graft rejection. HLA matching between recipient and unrelated donors, in particular, is important in improving outcomes in...
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