Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of 28 human embryonic stem cell lines for use as unrelated donors in stem cell therapy: implications of HLA and ABO genotypes.

Cell transplantation - 1 Jan 2010

Lee Jeoung Eun, Kang Myung Seo, Park Myoung Hee, Shim Sung Han, Yoon Tae Ki, Chung Hyung Min, Lee Dong Ryul

Abstract excerpt

For human embryonic stem cells (hESCs) to be used clinically, it is imperative that immune responses evoked by hESCs and their derivates after transplantation should be prevented. Human leukocyte antigens (HLA) and ABO blood group antigens are important histocompatibility factors in graft rejection. HLA matching between recipient and unrelated donors, in particular, is important in improving outcomes in...

Topics

ABO Blood-Group System
Alleles
Blood Grouping and Crossmatching
Cell Line
Embryonic Stem Cells
Fetal Blood
Genotype
HLA Antigens
Hematopoietic Stem Cell Transplantation
Histocompatibility Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Polymorphism, Restriction Fragment Length

Sequence Analysis, DNA

Tissue Donors

Source

Identifiers

PMID: 20587141
DOI: 10.3727/096368910X513991

Genes

ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20587141-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of 28 human embryonic stem cell lines for use as unrelated donors in stem cell therapy: implications of HLA and ABO genotypes.PMID 20587141Read ↗

HLA Matching in Unrelated Stem Cell Transplantation up to DateSemantic proximity Read ↗

Hematopoietic stem cell transplants from unrelated donorsSemantic proximity Read ↗

HLA-Matching Potential of an Established Human Embryonic Stem Cell Bank in ChinaSemantic proximity Read ↗

Distributions of HLA-A, -B, and -DRB1 alleles typed by amplicon-based next generation sequencing in Korean volunteer donors for unrelated hematopoietic stem cell transplantation.Semantic proximity Read ↗

Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor. Japan Marrow Donor Program.Semantic proximity Read ↗

Genome editing HLA alleles for a pilot immunocompatible hESC line in a Chinese hESC bank for cell therapies.Semantic proximity Read ↗

HLA-DRB1,3,4,5 and -DQB1 allele frequencies and HLA-DR/DQ linkage disequilibrium of 231 German caucasoid patients and their corresponding 821 potential unrelated stem cell transplants.Semantic proximity Read ↗

HLA matching in allogeneic stem cell transplantationSemantic proximity Read ↗

How to select the best available related or unrelated donor of hematopoietic stem cells?Semantic proximity Read ↗

Concise Review: One Stone for Multiple Birds: Generating Universally Compatible Human Embryonic Stem CellsSemantic proximity Read ↗

[Influence of HLA-A/B/C/DRB1/DQB1 on unrelated donor hematopoietic stem cell transplantation].Semantic proximity Read ↗

The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.