Article
8q24 sequence variants in relation to prostate cancer risk among men of African descent: a case-control study.
BMC cancer - 28 Jun 2010
Benford Marnita L, VanCleave Tiva T, Lavender Nicole A, Kittles Rick A, Kidd LaCreis R
Abstract excerpt
BACKGROUND: Human chromosome 8q24 has been implicated in prostate tumorigenesis. METHODS: Consequently, we evaluated seven 8q24 sequence variants relative to prostate cancer (PCA) in a case-control study involving men of African descent. Genetic alterations were detected in germ-line DNA from 195 incident PCA cases and 531 controls using TaqMan polymerase chain reaction (PCR). RESULTS: Inheritance of the 8q24...
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