Article
Liver grafts contain a unique subset of natural killer cells that are transferred into the recipient after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Jul 2010
Moroso Viviana, Metselaar Herold J, Mancham Shanta, Tilanus Hugo W, Eissens Diana, van der Meer Arnold, van der Laan Luc J W, Kuipers Ernst J, Joosten Irma, Kwekkeboom Jaap
Abstract excerpt
In contrast to other solid organ transplantations, liver grafts have tolerogenic properties. Animal models indicate that donor leukocytes transferred into the recipient after liver transplantation (LTX) play a relevant role in this tolerogenic phenomenon. However, the specific donor cell types involved in modulation of the recipient alloresponse are not yet defined. We hypothesized that this unique property of...
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