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Article

Detection of androgen receptor mutations in circulating tumor cells in castration-resistant prostate cancer.

Clinical chemistry - 1 Sept 2010

Jiang Yuqiu, Palma John F, Agus David B, Wang Yixin, Gross Mitchell E

Abstract excerpt

BACKGROUND: Coding mutations in the AR (androgen receptor) gene have been identified in tissue samples from patients with advanced prostate cancer and represent a possible mechanism underlying the development of castration-resistant prostate cancer (CRPC). There is a paucity of tumor-derived tissue available for molecular studies of CRPC patients. Circulating tumor cells (CTCs) in the blood of CRPC patients...

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Identifiers

PMID: 20581083
DOI: 10.1373/clinchem.2010.143297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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