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Article

African descents are more sensitive than European descents to the antitumor compounds α-hederin and kalopanaxsaponin I.

Planta medica - 1 Nov 2010

Feller Geva, Kugel Aleksandra, Moonshine Dana, Chalifa-Caspi Vered, Scholz Martin, Prüfer Dirk, Rabinski Tatiana, Müller Kai J, Ofir Rivka

Abstract excerpt

α-Hederin, a natural triterpene saponin and its derivative kalopanaxsaponin I (ksI) exhibit cytotoxicity against various cancer cell lines and IN VIVO tumors. We studied the genetic variants contributing to the activity of these two anticancer compounds. Cell lines derived from 30 trios of Europe...

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Identifiers

PMID: 20577945
DOI: 10.1055/s-0030-1250061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20577945-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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