Article
Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies?
The pharmacogenomics journal - 1 Oct 2013
Loh M, Chua D, Yao Y, Soo R A, Garrett K, Zeps N, Platell C, Minamoto T, Kawakami K, Iacopetta B, Soong R
Abstract excerpt
Inter-ethnic differences in drug handling and frequencies of pharmacogenetic variants are increasingly being characterized. In this study, we systematically assessed the feasibility of inferring ethnic trends in chemotherapy outcomes from inter-ethnic differences in pharmacogenetic variant frequencies. Frequencies of 51 variants and chemotherapy outcomes of East Asian and Caucasian colorectal cancer patients on...
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