Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcobalamin II receptor polymorphisms are associated with increased risk for neural tube defects.

Journal of medical genetics - 1 Oct 2010

Pangilinan F, Mitchell A, VanderMeer J, Molloy A M, Troendle J, Conley M, Kirke P N, Sutton M, Sequeira J M, Quadros E V, Scott J M, Mills J L, Brody L C

Abstract excerpt

OBJECTIVE: Women who have low cobalamin (vitamin B(12)) levels are at increased risk for having children with neural tube defects (NTDs). The transcobalamin II receptor (TCblR) mediates uptake of cobalamin into cells. Inherited variants in the TCblR gene as NTD risk factors were evaluated. METHOD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Cohort Studies
Share to Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Ireland

Share to Neural Tube Defects

Share to Receptors, Cell Surface

Share to Transcobalamins

Source

Open in PubMed Open full text

Identifiers

PMID: 20577008
DOI: 10.1136/jmg.2009.073775
PMCID: PMC4112773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20577008-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcobalamin II receptor polymorphisms are associated with increased risk for neural tube defects.PMID 20577008Read ↗

Evaluation of transcobalamin II polymorphisms as neural tube defect risk factors in an Irish population.Semantic proximity Read ↗

Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association.Semantic proximity Read ↗

Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects.Semantic proximity Read ↗

Association of Transcobalamin II (TCN2) and Transcobalamin II-Receptor (TCblR) Genetic Variations With Cobalamin Deficiency Parameters in Elderly Women.Semantic proximity Read ↗

Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects.Semantic proximity Read ↗

Analysis of the human folate receptor beta gene for an association with neural tube defects.Semantic proximity Read ↗

Transcobalamin II deficiency in twins with a novel variant in the TCN2 gene: case report and review of literature.Semantic proximity Read ↗

The transcobalamin (TCN2) 776C>G polymorphism affects homocysteine concentrations among subjects with low vitamin B(12) status.Semantic proximity Read ↗

Association between the MTHFR (rs1801133) gene variation and serum trace elements levels (Copper and Zinc) in individuals diagnosed with neural tube defects.Semantic proximity Read ↗

An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1).Semantic proximity Read ↗

Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population.Semantic proximity Read ↗

Transcobalamin and methionine synthase reductase mutated polymorphisms aggravate the risk of neural tube defects in humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.