Article
Receptor specificity and transmission of H2N2 subtype viruses isolated from the pandemic of 1957.
PloS one - 21 Jun 2010
Pappas Claudia, Viswanathan Karthik, Chandrasekaran Aarthi, Raman Rahul, Katz Jacqueline M, Sasisekharan Ram, Tumpey Terrence M
Abstract excerpt
Influenza viruses of the H2N2 subtype have not circulated among humans in over 40 years. The occasional isolation of avian H2 strains from swine and avian species coupled with waning population immunity to H2 hemagglutinin (HA) warrants investigation of this subtype due to its pandemic potential. In this study we examined the transmissibility of representative human H2N2 viruses, A/Albany/6/58 (Alb/58) and A/El...
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