Article
Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin.
PloS one - 1 Jan 2013
Srinivasan Karunya, Raman Rahul, Jayaraman Akila, Viswanathan Karthik, Sasisekharan Ram
Abstract excerpt
In the context of recently emerged novel influenza strains through reassortment, avian influenza subtypes such as H5N1, H7N7, H7N2, H7N3 and H9N2 pose a constant threat in terms of their adaptation to the human host. Among these subtypes, it was recently demonstrated that mutations in H5 and H9 hemagglutinin (HA) in the context of lab-generated reassorted viruses conferred aerosol transmissibility in ferrets (a...
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