Article
Proteomic analysis of hyphae-specific proteins that are expressed differentially in cakem1/cakem1 mutant strains of Candida albicans.
Journal of microbiology (Seoul, Korea) - 1 Jun 2010
Lee Kang-Hoon, Kim Seung-Yeop, Jung Jong-Hwan, Kim Jinmi
Abstract excerpt
The yeast-to-hyphal transition is a major virulence factor in the fungal pathogen Candida albicans. Mutations in the CaKEM1 gene, which encodes a 5'-3' exoribonuclease responsible for mRNA degradation, show a defect in hyphal growth. We applied two-dimensional gel electrophoresis to identify hyphae-specific proteins that have altered expressions in the presence of the cakem1 mutation. Eight proteins, Eno1, Eps1,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
