Article
Toxicology of monocrotophos.
Reviews of environmental contamination and toxicology - 1 Jan 1994
Skripsky T, Loosli R
Abstract excerpt
Monocrotophos is a water-soluble organophosphate insecticide with high oral and moderate dermal toxicity. The toxicologically relevant mode of action is the inhibition of ChE activities. The toxicity of organophosphate metabolites of monocrotophos is comparable with the parent compound. Glycol conjugation in plant metabolism decreased the acute toxicity significantly. Dephosphorylated metabolites showed no...
Topics
- Animals
- Carcinogens
- Dogs
- Female
- Humans
- Lethal Dose 50
- Mice
- Monocrotophos
- Mutation
- Neurotoxins
- Pest Control
- Pregnancy
- Rabbits
