Article
RIPK1 and CASP7 polymorphism as prognostic markers for survival in patients with colorectal cancer after complete resection.
Journal of cancer research and clinical oncology - 1 Apr 2011
Chae Yee Soo, Kim Jong Gwang, Sohn Sang Kyun, Lee Su Jeong, Kang Byung Woog, Moon Joon Ho, Park Jae Yong, Jeon Seong Woo, Bae Han-Ik, Choi Gyu Seog, Jun Soo-Han
Abstract excerpt
BACKGROUND: Since apoptosis plays a key role in cancer progression, the present study analyzed the polymorphisms of apoptosis-related genes and their impact on survival after curative resection in patients with colorectal cancer. MATERIALS AND METHODS: Three hundred and seventy-seven patients were enrolled in the present study. The genomic DNA was extracted from fresh colorectal mucosal tissue, and 15 SNPs of 12...
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