Article
Association between LEP and LEPR gene polymorphisms and dyslipidemia in patients using atypical antipsychotic medication.
Psychiatric genetics - 1 Dec 2010
Gregoor Jochem G, van der Weide Jan, Loovers Harriet M, van Megen Harold J, Egberts Toine C, Heerdink Eibert R
Abstract excerpt
BACKGROUND: Treatment with atypical antipsychotic agents is often complicated by dyslipidemia, which is a risk factor for cardiovascular disease. OBJECTIVES: To determine whether the LEPR Q223R, the LEP -2548G/A, and the HTR2C -759C/T polymorphisms are associated with dyslipidemia in patients using atypical antipsychotic drugs. METHODS: A cross-sectional study design was used. The study population included all...
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