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Article

Polymorphisms of the LEP- and LEPR gene and obesity in patients using antipsychotic medication.

Journal of clinical psychopharmacology - 1 Feb 2009

Gregoor Jochem G, van der Weide Jan, Mulder Hans, Cohen Dan, van Megen Harold J G M, Egberts Antoine C G, Heerdink Eibert R

Abstract excerpt

Weight gain is one of the most serious adverse effects of atypical antipsychotic agents. Genetic factors influence the risk of an individual to gain weight. The objective of our study was to determine whether the LEPR Q223R polymorphism and the LEP promoter 2548G/A polymorphism are associated wit...

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Source

Identifiers

PMID: 19142102
DOI: 10.1097/JCP.0b013e31819359be

Genes

LEPR
LEP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19142102-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Polymorphisms of the LEP- and LEPR gene and obesity in patients using antipsychotic medication.PMID 19142102Read ↗

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