Article
Identification of HLA-DP3-restricted peptides from EBNA1 recognized by CD4(+) T cells.
Cancer research - 15 Dec 2002
Voo Kui Shin, Fu Tihui, Heslop Helen E, Brenner Malcolm K, Rooney Cliona M, Wang Rong-Fu
Abstract excerpt
The EBV-encoded nuclear antigen 1 (EBNA1) is required for the maintenance and replication of the viral episome in EBV-transformed human B-lymphoblastoid cell lines. It is expressed in all EBV-associated tumors, making it a potentially important target for immunotherapy. However, this promise has...
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