Article
A flagella-less mutant of Borrelia burgdorferi. Structural, molecular, and in vitro functional characterization.
The Journal of clinical investigation - 1 Jul 1991
Sadziene A, Thomas D D, Bundoc V G, Holt S C, Barbour A G
Abstract excerpt
A nonmotile mutant of Borrelia burgdorferi, the etiologic agent of Lyme disease, was isolated and characterized. The mutant was compared with the wild-type predecessor as well as with a motile back-revertant of the same genetic background. The mutant lacked, by morphologic, biochemical, and immunologic criteria, the major structural protein of flagella, flagellin. This mutation was not associated with major DNA...
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